ChemicalBook > CAS DataBase List > 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE

3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE

Product Name
3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
CAS No.
218137-86-1
Chemical Name
3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
Synonyms
C75;FAS inhibitor C75 (C-75;C75 >=98% (HPLC), powder;3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE;TRANS-4-CARBOXY-5-OCTYL-3-METHYLENEBUTYROLACTONE;3-Furancarboxylic acid, tetrahydro-4-methylene-2-octyl-5-oxo-;C75(4-Methylene-2-octyl-5-oxo-tetrahydro-furan-3-carboxylicacid);TRANS-TETRAHYDRO-3-METHYLENE-2-OXO-5-N-OCTYL-4-FURANCARBOXYLIC ACID
CBNumber
CB2114165
Molecular Formula
C14H22O4
Formula Weight
254.32
MOL File
218137-86-1.mol
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3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Property

Boiling point:
432.1±45.0 °C(Predicted)
Density 
1.08±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 18 mg/mL
form 
solid
pka
3.08±0.40(Predicted)
color 
off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C5490
Product name
C75
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$345
Updated
2024/03/01
Sigma-Aldrich
Product number
C5490
Product name
C75
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$1390
Updated
2024/03/01
Tocris
Product number
2489
Product name
C75
Purity
≥99%(HPLC)
Packaging
10
Price
$227
Updated
2021/12/16
Usbiological
Product number
254848
Product name
C 75
Packaging
10mg
Price
$480
Updated
2021/12/16
ChemScene
Product number
CS-3562
Product name
C75
Purity
99.91%
Packaging
50mg
Price
$842
Updated
2021/12/16
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3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Chemical Properties,Usage,Production

Uses

C75 has been used:

  • as a fatty acid synthase (FASN) inhibitor to test its ability in the direct inhibition of FASN to attenuate mammosphere formation as compared to metformin
  • as a pharmacological inhibitor to inhibit fatty acid synthesis in glioma stem cells (GSCs)
  • as FAS inhibitor in the pre-treatment of Chang cells to inhibit lipogenesis and reverse the senescence induced by hydrogen peroxide

Definition

ChEBI: 4-methylene-2-octyl-5-oxo-3-oxolanecarboxylic acid is a gamma-lactone.

Biochem/physiol Actions

C75 helps to increase the cancer‐killing capability of ionizing radiation.

3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Suppliers

CHINA 42 Switzerland 1 United States 13 Global 56
AdooQ BioScience, LLC
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BOC Sciences
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218137-86-1, 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONERelated Search:

BUTTPARK 27\04-75 BUTTPARK 4\01-75 BUTTPARK 30\09-75 BUTTPARK 23\07-75 BUTTPARK 32\01-75 BUTTPARK 35\03-75 BUTTPARK 31\08-75 BUTTPARK 43\57-75 BUTTPARK 33\08-75 BUTTPARK 18\01-75 BUTTPARK 153\33-75 BUTTPARK 34\07-75 BUTTPARK 37\11-75 BUTTPARK 29\09-75 16:0 PC D75 BUTTPARK 16\04-75 BUTTPARK 26\07-75 BUTTPARK 152\40-75

  • 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
  • C75
  • C75(4-Methylene-2-octyl-5-oxo-tetrahydro-furan-3-carboxylicacid)
  • TRANS-4-CARBOXY-5-OCTYL-3-METHYLENEBUTYROLACTONE
  • TRANS-TETRAHYDRO-3-METHYLENE-2-OXO-5-N-OCTYL-4-FURANCARBOXYLIC ACID
  • FAS inhibitor C75 (C-75
  • 3-Furancarboxylic acid, tetrahydro-4-methylene-2-octyl-5-oxo-
  • C75 >=98% (HPLC), powder
  • 218137-86-1
  • Fatty acid synthase
  • Enzyme Inhibitors by Enzyme
  • Enzymes, Inhibitors, and Substrates
  • D to K
  • Enzyme Inhibitors
  • Biochemicals and Reagents
  • BioChemical